Instrumen untuk mengukur distribusi ukuran partikel dalam suspensi. Instrumen ini memanfaatkan perilaku hamburan cahaya ketika sinar laser melewati sekelompok partikel. Distribusi ukuran dihitung dengan mengukur sudut cahaya yang dihamburkan oleh partikel dengan berbagai ukuran.
Sizing of colloidal silica is a critical requirement. This is easily and reproducibly measured using the Zetasizer Lab Blue Label.
Titanium dioxide use wide-ranging. When used in paints or inks, agglomerate or aggregate formation can diminish product performance.
The Zetasizer Pro Blue Label, used alongside the MPT-3 Autotitrator, characterizes the impact of salt concentration on the stability of TiO2 and identifies the most stable pH region.
The strength of ceramics is linked to particle size, and the Zetasizer Ultra Blue Label is ideally placed to measure this. Al2O3 samples are often made of differently-sized particles which can easily be identified using MADLS. In this 0,1% w/v sample, the two particle size populations would not be distinguishable with a single angle DLS measurement.
For protein researchers, early access to characterization date can be a challenge, due to low sample volumes. This is easily overcome using the Zetasizer Lab Red Label with the capillary cell to confirm that samples meet quality requirements and that production and purificatio processes are optimized.
Photoluminescent C-dots are considered safer alternatives to quantum dots. Measuring fluorescent sample by DLS can be challeinging due to additional photons emitted by the fluorophore. Available with NIBS on Zetasizer Pro Red Label, a filter removes this interference to provide accurate and reliable data.
Monitoring viral concentration is important during development and production optimization. By using the Multi-Angle DLS (MADLS) based particle concentration measurement in the Zetasizer Ultra Red Label, both the size distribution and titer of the virus can be measured within a few minutes.
| Size Measurement Principle |
|
| Zeta Measurement Principle | ELS with M3-PALS and Constant Current Zeta Mode |
| Molecular Weight and B221 | Static Light Scattering (173°) |
| Optical Filter Wheel (Fluorescence/DDLS) | Yes |
| Low Volume Disposable Sizing Cell with Extended Size Analysis Support | No |
| MADLS® (High Resolution DLS) | No |
| MADLS® - Particle Concentration/Titer | No |
| 21 CFR Part 11 Compliant Software2 | Optional |
| Range3 | 0.3 nm to 10 μm |
| Minumum Volume | 12 μL |
| Size Range | 3.8 nm to 100 μm |
| Minumum Volume4 | 20 μL |
1 Hardware capable; Software support coming soon
2 21 CFR Part 11 software features coming soon
3 0 μm by default. Option to extend for Zetasizer Lab and Zetasizer Ultra coming soon
4 Patented Diffusion Barrier method in capillary cell
| Sample | : Silica Gel |
| Material Refractive Index | : 1.45 |
| Material Absorption | : 0.001 |
| Dispersant Name | : Water |
| Dispersant Refractive Index | : 1.33 |
| Dispersant Viscosity | : 0.887 |
| Dispersant Dielectric Const. | : 78.5 |
| Cell Type | : DTS1070 |
| Z-Average (nm) | : 627.8 |
| Polydispersity Index (PI) | : 0.4971 |
| Peak 1 Mean by Number Ordered by Size (nm) | : 421 |
| Peak 1 Area by Number Ordered by Size (&) | : 100 |
| Satuan Layanan | Contract |
| Duration | 30 minutes/sample |
| Sample Type | Solutions or dispersant |
| Measurement Angles | 173’, 13’ |
| Range (Diameter) | 0,3 nm- 10 µm |
| Min. Sample | 12 µL |
| Concentration | 40% w/v |
| Range (Diameter) | 3.8 nm- 100 µm |
| Zeta Potential Range | No effective limitations |
| Mobility Range | >+/- 20 µ.cm/V.s |
| Min Sample Volume & Min Sample Concentration | 20 µL & 10 mg/mL |
| Max Sample Concentratiom & Max sample conductivity | 40% w/v & 260 mS/cm |
| Conductivity Accurancy | ±10% |
Zetasizer systems include NIBSTM technology, which combines back-scatter detection with variable measurement positioning and high efficiency fiber optic technology. Application examples : Colloidal Silica, Titanium Dioxide, Ceramics, Proteins, Carbon Dots (C-dots), Adeno-Associated Virus (AAV).
new Zetasizer Pro is your go-to instrument to measure a wide range of sample types and concentrations. It offers wide dynamic concentration capability and high sensitivity due to the Non-Invasive Back Scatter (NIBS) optical design. Measurement of particle size, molecular size, electrophoretic mobility, zeta potential and molecular weight can all be performed with ease. .
Adaptive Correlation feature enhances sample throughput by reducing measurement duration and providing greater sample knowledge. The deep learning-based data quality system gives you the confidence to know your data is the best it can be.
optical filter wheel allows measurement of fluorescent samples without impacting overall instrument sensitivity.
| PSA |
| IDR550.000 |
| Zeta Potential |
| IDR800.000 |
